Dynamics of the spontaneous formation of a planar phospholipid bilayer: A new approach by simultaneous electrical and optical measurements

摘要: An artificial lipid bilayer in planar form, well known as membrane (BLM), spontaneously forms from a droplet (L-α-phosphatidylcholine n-decane and chloroform this work) an aperture of thin partition aqueous solution. The thinning dynamics the or has been studied by simultaneous capacitance image recording, because sandwiched solutions can be considered parallel-plate capacitor. measurements have revealed two-step its specific value: first, initial thins to yield about 100 nm thickness (0.02 μF/cm2), second, within membrane, 4 (0.42 μF/cm2) suddenly emerges grows, keeping structure. In addition, time stamp, thus determine trigger moment formation. provides first ...