The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans

作者: Ulrike Binder , Christoph Oberparleiter , Vera Meyer , Florentine Marx

DOI: 10.1111/J.1365-2958.2009.06936.X

关键词: Platelet-activating factorActivator (genetics)Protein kinase CProtein kinase AFungal proteinAspergillus nidulansRHOACell biologyEnzyme activatorBiologyBiochemistry

摘要: … by activation of the Pka signalling cascade. Our findings thus indicate that PAF interferes with at least two distinct signalling pathways, namely cAMP/Pka and Pkc/Mpk signalling. …

参考文章(57)
D Michael Gill, Marilyn Woolkalis, [32P]ADP-ribosylation of proteins catalyzed by cholera toxin and related heat-labile enterotoxins. Methods in Enzymology. ,vol. 165, pp. 235- 245 ,(1988) , 10.1016/S0076-6879(88)65037-3
Van R. Potter, Fred R. Butcher, Control of the Adenosine 3′,5′-Monophosphate-Adenyl Cyclase System in the Livers of Developing Rats Cancer Research. ,vol. 32, pp. 2141- 2147 ,(1972)
Kaihei Kojima, Yoshitaka Takano, Akira Yoshimi, Chihiro Tanaka, Taisei Kikuchi, Tetsuro Okuno, Fungicide activity through activation of a fungal signalling pathway. Molecular Microbiology. ,vol. 53, pp. 1785- 1796 ,(2004) , 10.1111/J.1365-2958.2004.04244.X
Robbert A. Damveld, Mark Arentshorst, Angelique Franken, Patricia A. VanKuyk, Frans M. Klis, Cees A. M. J. J. Van Den Hondel, Arthur F. J. Ram, The Aspergillus niger MADS-box transcription factor RlmA is required for cell wall reinforcement in response to cell wall stress. Molecular Microbiology. ,vol. 58, pp. 305- 319 ,(2005) , 10.1111/J.1365-2958.2005.04827.X
H. Nonaka, K. Tanaka, H. Hirano, T. Fujiwara, H. Kohno, M. Umikawa, A. Mino, Y. Takai, A Downstream Target of RHO1 Small GTP-binding Protein Is PKC1, a Homolog of Protein Kinase C, Which Leads to Activation of the MAP Kinase Cascade in Saccharomyces Cerevisiae The EMBO Journal. ,vol. 14, pp. 5931- 5938 ,(1995) , 10.1002/J.1460-2075.1995.TB00281.X
Robbert A. Damveld, The cell wall of the filamentous fungus Aspergillus niger Institute of Biology, Faculty of Mathematics & Natural Sciences, Leiden University. ,(2005)
Mojca Benčina, Matic Legiša, Nick D. Read, Cross-talk between cAMP and calcium signalling in Aspergillus niger Molecular Microbiology. ,vol. 56, pp. 268- 281 ,(2005) , 10.1111/J.1365-2958.2005.04541.X
M-C Soulié, A Piffeteau, M Choquer, M Boccara, A Vidal-Cros, None, Disruption of Botrytis cinerea class I chitin synthase gene Bcchs1 results in cell wall weakening and reduced virulence. Fungal Genetics and Biology. ,vol. 40, pp. 38- 46 ,(2003) , 10.1016/S1087-1845(03)00065-3