Effects of Low Temperature Plasmas on Cancer Cells

作者: Nazir Barekzi , Mounir Laroussi

DOI: 10.1002/PPAP.201300083

关键词: ApoptosisReactive nitrogen speciesEnvironmental chemistryOxidative phosphorylationCancer cellLeukemiaCancerSignal transductionBiophysicsChemistryReactive oxygen species

摘要: Biologically tolerant plasmas (BTPs) are with gas temperatures less than 40 °C that generated near atmospheric pressures and in non-toxic gases such as air or helium. BTPs have recently garnered great interest a therapeutic for cancer. Here, we review discuss conventional cancer treatments, some of the plasma devices currently used influence on cells melanomas, carcinomas, leukemia. The active agents been investigated reveal presence reactive oxygen species (ROS) O, O2−, O3, OH well nitrogen (RNS) NO NO2. ROS RNS exhibit oxidative properties trigger signaling pathways biological cells. In cells, different doses induce including apoptosis.

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