Effects of Experimental Sleep Restriction on Caloric Intake and Activity Energy Expenditure

摘要: Background Epidemiologic studies link short sleep duration to obesity and weight gain. Insufficient appears alter circulating levels of the hormones leptin ghrelin, which may promote appetite, although effects restriction on caloric intake energy expenditure are unclear. We sought determine effect 8 days/8 nights intake, activity expenditure, ghrelin. Methods conducted a randomized study usual vs two-thirds normal time for in hospital-based clinical research unit. The main outcomes were Results Caloric sleep-restricted group increased by +559 kcal/d (SD, 706 kcal/d, P = .006) decreased control −118 386 .51) net change +677 (95% CI, 148-1,206 kcal/d; .014). Sleep was not associated with changes ( .62). No seen .27) or ghrelin .21). Conclusions an increase consumption no concentrations. Increased without any accompanying contribute people who exposed long-term restriction. Trial Registration ClinicalTrials.gov ; No.: NCT01334788 URL: www.clinicaltrials.gov