Alcoholic Beverage Intake and Risk of Lung Cancer: The California Men's Health Study

摘要: We investigated the effect of alcoholic beverage consumption on risk lung cancer using California Men's Health Study. Methods: The Study is a multiethnic cohort 84,170 men ages 45 to 69 years who are members Kaiser Permanente health plans. Demographics and detailed lifestyle characteristics were collected from surveys mailed between 2000 2003. Incident cases identified by plan registries through December 2006 ( n = 210). Multivariable Cox's regression was used examine effects beer, red wine, white wine (including rose), liquor adjusting for age, race/ethnicity, education, income, body mass index, history chronic obstructive pulmonary disease/emphysema, smoking history. Results: There significant linear decrease in associated with among ever-smokers: hazard ratio (HR), 0.98; 95% confidence interval (95% CI), 0.96-1.00 increase 1 drink per month. This relationship slightly stronger heavy smokers (≥20 pack-years): HR, 0.96; CI, 0.93-1.00. When examined frequency intake, ≥1 day an approximately 60% reduced 0.39; 0.14-1.08. No clear associations seen intake or liquor. Conclusion: Moderate inversely after confounders. Our results should not be extrapolated alcohol consumption. (Cancer Epidemiol Biomarkers Prev 2008;17(10):2692–9)