作者: Catherine L. Carpenter , Hal Morgenstern , Stephanie J. London
DOI: 10.1093/JN/128.4.694
关键词: Case-control study 、 Risk factor 、 Saturated fat 、 Gerontology 、 Confounding 、 Odds ratio 、 Confidence interval 、 Alcoholic beverage consumption 、 Environmental health 、 Medicine 、 Population
摘要: Although studies generally support a positive association between alcohol consumption and lung-cancer risk, the relationship specific alcoholic beverages risk has been inconsistent. We examined recent past beverage intake among 261 incident cases 615 population controls enrolled in case-control study of African Americans Caucasians Los Angeles County 1991 1994. An in-person interview elicited information about from ages 30 to 40 y, smoking, other factors, as well alcohol, dietary intake. was observed hard-liquor risk. The odds ratio (OR) for 1 or more drinks (1.5 oz 0.051 mL) per day hard liquor compared with infrequent drinking (0-3 month), adjusted matching saturated fat 1.87 [95% confidence interval (CI) = 1.02-3.42]. No appreciable total whereas small inverse associations were beer wine, although intervals wide. elevated also (between y). OR drinkers 1.83 (95% CI 1. 06-3.15). Confounding lung cancer by smoking apparent. we devoted considerable efforts adjusting our analyses, residual confounding is still possible because are closely associated. In addition, including this should be viewed caution selection bias. increased might occur moderate but confirmation required larger studies.