Induction and regulation of IFNs during viral infections.

作者: Lene Malmgaard

DOI: 10.1089/1079990041689665

关键词: ImmunologyImmune systemCellular differentiationAntigen presentationCytokineReceptorCell biologyAcquired immune systemBiologyNFATSignal transduction

摘要: … In contrast, IFN-γ is induced by receptor-mediated … Cytokine and TCR-induced IFN-γ expression uses distinct signal … This review focuses on the latest findings regarding induction and …

参考文章(201)
HOWARD A. YOUNG, Regulation of interferon-gamma gene expression. Journal of Interferon and Cytokine Research. ,vol. 16, pp. 563- 568 ,(1996) , 10.1089/JIR.1996.16.563
Jianfei Yang, Hong Zhu, Theresa L. Murphy, Wenjun Ouyang, Kenneth M. Murphy, IL-18–stimulated GADD45β required in cytokine-induced, but not TCR-induced, IFN-γ production Nature Immunology. ,vol. 2, pp. 157- 164 ,(2001) , 10.1038/84264
Evelyn A. Kurt-Jones, Lana Popova, Laura Kwinn, Lia M. Haynes, Les P. Jones, Ralph A. Tripp, Edward E. Walsh, Mason W. Freeman, Douglas T. Golenbock, Larry J. Anderson, Robert W. Finberg, Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus Nature Immunology. ,vol. 1, pp. 398- 401 ,(2000) , 10.1038/80833
Naohiro Inohara, Gabriel Nuñez, NODs: intracellular proteins involved in inflammation and apoptosis. Nature Reviews Immunology. ,vol. 3, pp. 371- 382 ,(2003) , 10.1038/NRI1086
Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai, Tsuneyasu Kaisho, Shintaro Sato, Hideki Sanjo, Makoto Matsumoto, Katsuaki Hoshino, Hermann Wagner, Kiyoshi Takeda, Shizuo Akira, A Toll-like receptor recognizes bacterial DNA. Nature. ,vol. 408, pp. 740- 745 ,(2000) , 10.1038/35047123
Mohammed Soutto, Feng Zhang, Ben Enerson, Yingkai Tong, Mark Boothby, Thomas M. Aune, A Minimal IFN-γ Promoter Confers Th1 Selective Expression The Journal of Immunology. ,vol. 169, pp. 4205- 4212 ,(2002) , 10.4049/JIMMUNOL.169.8.4205
Miren Kerkmann, Simon Rothenfusser, Veit Hornung, Andreas Towarowski, Moritz Wagner, Anja Sarris, Thomas Giese, Stefan Endres, Gunther Hartmann, Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells Journal of Immunology. ,vol. 170, pp. 4465- 4474 ,(2003) , 10.4049/JIMMUNOL.170.9.4465
Cristina M. Tato, Alejandro Villarino, Jorge H. Caamaño, Mark Boothby, Christopher A. Hunter, Inhibition of NF-κB Activity in T and NK Cells Results in Defective Effector Cell Expansion and Production of IFN-γ Required for Resistance toToxoplasma gondii The Journal of Immunology. ,vol. 170, pp. 3139- 3146 ,(2003) , 10.4049/JIMMUNOL.170.6.3139
J. David Farrar, Janice D. Smith, Theresa L. Murphy, Stewart Leung, George R. Stark, Kenneth M. Murphy, Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nature Immunology. ,vol. 1, pp. 65- 69 ,(2000) , 10.1038/76932