A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part V. Evaluation of the antimalarial activity of plants used by the Tacana Indians.
作者： E Deharo , G Bourdy , C Quenevo , V Muñoz , G Ruiz
DOI: 10.1016/S0378-8741(01)00270-7
关键词: Phytotherapy 、 Pharmacognosy 、 Plasmodium falciparum 、 Traditional medicine 、 Ethnobotany 、 Biology 、 Medicinal plants 、 Antimalarial Agent 、 Aspidosperma 、 Bark 、 Botany
摘要: Seventy-seven plant extracts (corresponding to 62 different species) traditionally used by the Isoceno-Guarani, a native community living in Bolivian Chaco, were screened for antimalarial activity vitro on Plasmodium falciparum chloroquine sensitive strain (F32), and ferriprotoporphyrin (FP) IX biocrystallisation inhibition test (FBIT). Among these extracts, seven displayed strong activity, 25 active FBIT test. Positive results both tests recorded six extracts: Argemone subfusiformis aerial part, Aspidosperma quebracho-blanco bark, Castela coccinea leaves Solanum argentinum Vallesia glabra bark. Results are discussed relation with Isoceno-Guarani traditional medicine. Further studies be undertaken also highlighted.
cabdirect.org
elsevier.com
sci-hub.se 参考文章(82)
Sevser Sahpaz, Ch. Bories, P. Loiseau, D. Cortès, R. Hocquemiller, A. Laurens, A. Cavé, Cytotoxic and Antiparasitic Activity from Annona senegalensis Seeds Planta Medica. ,vol. 60, pp. 538- 540 ,(1994) , 10.1055/S-2006-959566
R. Ekong, S. J. Partridge, M. M. Anderson, G. C. Kirby, D. C. Warhurst, P. F. Russell, J. D. Phillipson, Plasmodium falciparum: effects of phaeanthine, a naturally-occurring bisbenzylisoquinoline alkaloid, on chloroquine-resistant and -sensitive parasites in vitro, and its influence on chloroquine activity. Annals of Tropical Medicine and Parasitology. ,vol. 85, pp. 205- 213 ,(1991) , 10.1080/00034983.1991.11812547
W. Peters, B. L. Robinson, S. L. Mutambu, D. C. Warhurst, D. S. Ellis, D. G. Tovey, The chemotherapy of rodent malaria. XLIV. Studies on the mode of action of CM 6606, an indolo (3,2-c) quinoline N-oxide. Annals of Tropical Medicine and Parasitology. ,vol. 83, pp. 1- 10 ,(1989) , 10.1080/00034983.1989.11812304
Kweifio-Okai G, De Munk F, Cropley M, Rumble Ba, Macrides Ta, Antiarthritic mechanisms of amyrin triterpenes. Research Communications in Molecular Pathology and Pharmacology. ,vol. 85, pp. 45- 55 ,(1994)
Tang Xy, Zhou Mh, Zhang Zh, Zhang Yb, Active constituents of Commelina communis L. China journal of Chinese materia medica. ,vol. 19, pp. 297- ,(1994)
W. Peters, B. L. Robinson, The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials Annals of Tropical Medicine & Parasitology. ,vol. 86, pp. 455- 465 ,(1992) , 10.1080/00034983.1992.11812694
E. Deharo, M. Sauvain, C. Moretti, B. Richard, E. Ruiz, G. Massiot, Activité antipaludique du N-hentriacontanol isolé de Cuatresia sp ( Solanaceae ) Annales de parasitologie humaine et comparée. ,vol. 67, pp. 126- 127 ,(1992) , 10.1051/PARASITE/1992674126
A. Ramahatra, D. Cortes, H. Dadoun, A. Cave, La bélémine, intermédiaire biogénétique potentiel des méthyl-7 aporphines Comptes-rendus des séances de l'Académie des sciences. Série 2, Mécanique-physique, chimie, sciences de l'univers, sciences de la terre. ,vol. 299, pp. 311- 314 ,(1984)
A. Velasco-Negueruela, M. J. Perez-Alonso, G. Esenarro Abarca, Medicinal plants from Pampallakta : an andean community in Cuzco (Peru) Fitoterapia. ,vol. 66, pp. 447- 461 ,(1995)
P. Hoet, Use of certain plants in the traditional pharmacopoeia of Peru. Plantes Medicinales et Phytotherapie. ,vol. 14, pp. 193- 201 ,(1980)