Surgical-Pathologic Risk Factors and Immunohistochemical Markers of Pelvic Lymph Node Metastasis in Stage IB1 Cervical Cancer
作者： Enrique Hernandez , José De La Mota , M. Bijoy Thomas , Yajue Huang , John P. Gaughan
DOI: 10.1097/LGT.0B013E31821C97DE
关键词: Parametrial 、 Adenosquamous carcinoma 、 Pathology 、 Adenocarcinoma 、 Medicine 、 Lymphovascular invasion 、 Internal medicine 、 Lymph 、 Stage (cooking) 、 Lymph node 、 Oncology 、 Cervical cancer 、 Obstetrics and gynaecology 、 General Medicine
摘要: Objective : This study aimed to identify the surgical-pathologic risk factors and immunohistochemical markers of pelvic lymph node metastasis in stage IB1 cervical cancer. Materials methods A retrospective review patients with cancer who underwent radical abdominal hysterectomy, dissection, staining for p53, bcl-2, Ki-67 was performed. Results total 29 complete clinical data pathology tissue blocks are subjects this study. Of these patients, 20 (69%) had squamous cell carcinoma, 8 (28%) adenocarcinoma, 1 (3%) adenosquamous carcinoma. The median tumor diameter as measured laboratory 2 cm. number nodes removed 24. Four (14%) positive nodes. Lymphovascular invasion noted 10 (34%). None 19 without lymphovascular involvement. (7%) parametrial There a statistically significant correlation between depth (r = 0.43, p .02), 0.55, .0019). immunostaining index higher and/or (p .008 .028, respectively). no association p53 or bcl-2 expression metastasis. Conclusions Lymph (14 %) involvement occurred only large size. is associated
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