Plasma total antioxidant capacity (TAC) in obese Malaysian subjects.

作者: Y H Say , S H Lim , S H Fan

DOI:

关键词: Blood plasmaTrolox equivalent antioxidant capacityEndocrinologyAnthropometryWaistInternal medicineObesityAntioxidantMedicineBody mass indexBlood pressure

摘要: Introduction There is a pressing need to better understand the complex biochemical pathways that lead pathogenesis of obesity. Increased oxidative stress and decreased antioxidant capacity have been identified be associated with Therefore, objectives this study were determine plasma total (TAC) levels Malaysian subjects evaluate its potential association obesity related anthropometric measurements. Methods Plasma TAC 362 multi-ethnic from Kampar Health Clinic (138 males, 224 females; 124 ethnic Malays, 152 Chinese, 86 Indians; 192 non-obese, 170 obese) was measured using Trolox equivalent (TEAC) 96-well plate assay. Results significantly lower in obese (M +/- SE = 292 10.4 micromol/L) compared non-obese (397 8.58 micromol/L), whereas it higher males those 21-30 age group. Those salty food preference practising strict vegetarian diet also had TAC. However, no found for other dietary habits (coffee intake) lifestyle factors (physical activity, smoking). negatively correlated diastolic blood pressure, waist hip circumferences, weight, body mass index, fat, % subcutaneous visceral fat level, resting metabolism skeletal muscle. Conclusion obesity, practice, all indicators, except systolic pressure pulse rate. Obese people indicating compromised systemic defence increased stress.

参考文章(25)
Nicoletta Pellegrini, Mauro Serafini, Barbara Colombi, Daniele Del Rio, Sara Salvatore, Marta Bianchi, Furio Brighenti, Total Antioxidant Capacity of Plant Foods, Beverages and Oils Consumed in Italy Assessed by Three Different In Vitro Assays Journal of Nutrition. ,vol. 133, pp. 2812- 2819 ,(2003) , 10.1093/JN/133.9.2812
Nicholas J Miller, Catherine Rice-Evans, Michael J Davies, Vimala Gopinathan, Anthony Milner, None, A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates Clinical Science. ,vol. 84, pp. 407- 412 ,(1993) , 10.1042/CS0840407
Barry Halliwell, John M.C. Gutteridge, The definition and measurement of antioxidants in biological systems Free Radical Biology and Medicine. ,vol. 18, pp. 125- 126 ,(1995) , 10.1016/0891-5849(95)91457-3
John Melissas, Niki Malliaraki, John Papadakis, Panagiotis Taflampas, Marilena Kampa, Elias Castanas, Plasma antioxidant capacity in morbidly obese patients before and after weight loss. Obesity Surgery. ,vol. 16, pp. 314- 320 ,(2006) , 10.1381/096089206776116444
Paresh Dandona, Priya Mohanty, Husam Ghanim, Ahmad Aljada, Richard Browne, Wael Hamouda, Anu Prabhala, Aqeela Afzal, Rajesh Garg, The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 355- 362 ,(2001) , 10.1210/JCEM.86.1.7150
Yasuhiro Kambayashi, Nguyen Thanh Binh, Hiroki W. Asakura, Yuri Hibino, Yoshiaki Hitomi, Hiroyuki Nakamura, Keiki Ogino, Efficient assay for total antioxidant capacity in human plasma using a 96-well microplate. Journal of Clinical Biochemistry and Nutrition. ,vol. 44, pp. 46- 51 ,(2009) , 10.3164/JCBN.08-162