First in vivo visualization of MRI-visible IPOM in a rabbit model

摘要: Background: Application of a mesh in presence pneumoperitoneum may cause deformation or wave formation when gas is released. Moreover, shrinkage during subsequent wound healing cannot be detected vivo without invasive diagnostics. Using MRI-visible polyvinylidene fluoride (PVDF) mesh, the extend and could objectified by MRI for first time. Materials Methods: Laparoscopic intraperitoneal onlay (IPOM) implantation was performed 10 female rabbits using ferro-oxide loaded PVDF meshes. measurements were postoperatively at days 1 90. After three-dimensional reconstruction all images total surface effective implanted explored calculated computer-assisted. Results: In cases, identified MRI. The always allowed calculation area. relation to original size used textile implant, we found neither significant reduction after release day laparoscopic surgery nor change this large pore end observation period. Conclusions: investigation via exclude initial pneumoperitoneum, IPOM rabbit model. A further these meshes excluded, as well. Imaging turned out sufficient tool objectify configuration position vivo. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 102B: 1165–1169, 2014.