A Convenient and General Method for the Synthesis of Indole‐2,3‐dicarboxylates and 2‐Arylindole‐3‐carboxylates
作者： Iliyas Ali Sayyed , Karolin Alex , Annegret Tillack , Nicolle Schwarz , Dirk Michalik
关键词: Domino 、 Organic chemistry 、 Chemistry 、 Indole test 、 Hydroamination 、 Fischerindole 、 General method 、 Acetylene
摘要: A transition-metal-free, simple and efficient one-pot method for the synthesis of indole-2,3-dicarboxylates 2-arylindole-3-carboxylates is described. The corresponding products are obtained by a domino hydroamination/Fischerindole cyclization in good-to-excellent yields from easily available 1-alkyl-1-phenylhydrazines acetylene carboxylates.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
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