The MAPK pathway across different malignancies: a new perspective.

作者: Mauricio Burotto , Victoria L. Chiou , Jung-Min Lee , Elise C. Kohn

DOI: 10.1002/CNCR.28864

关键词: MAPK/ERK pathwayMedicineCell biologyMelanomaMitogen-activated protein kinase kinaseKinaseProtein kinase BProto-Oncogene Proteins B-rafCancer researchCancerProtein kinase A

摘要: … There are 4 independent MAPK pathways composed of 4 signaling families: the MAPK/ERK family or classical pathway and the Big MAP kinase-1 (BMK-1), c-Jun N-terminal kinase (…

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