Interrelation between Neuroendocrine Disturbances and Medical Complications Encountered during Rehabilitation after TBI

摘要: Traumatic brain injury is not a discrete event but an unfolding sequence of damage to the central nervous system. Not only acute phase also subacute and chronic period after injury, i.e., during inpatient rehabilitation, characterized by multiple neurotransmitter alterations, cellular dysfunction, medical complications causing additional secondary injury. Neuroendocrine disturbances influence neurological outcome are easily overlooked as they often present with diffuse symptoms such fatigue, depression, poor concentration, or decline in overall cognitive function; these typical sequelae traumatic Furthermore, hydrocephalus, epilepsy, disorders consciousness, paroxysmal sympathetic hyperactivity, psychiatric-behavioural may mask and/or complicate diagnosis neuroendocrine disturbances, delay appropriate treatment impede neurorehabilitation. The review seeks examine interrelation between frequently encountered moderate severe TBI rehabilitation. Common their clinical implications discussed.