作者: Julie A. Champion , Samir Mitragotri
DOI: 10.1007/S11095-008-9626-Z
关键词: Drug delivery 、 Phagocytosis 、 Polymer particle 、 Pharmacology toxicology 、 Biophysics 、 Particle 、 Nanotechnology 、 Macrophage 、 Chemistry
摘要: Purpose To determine if particle shape can be engineered to inhibit phagocytosis of drug delivery particles by macrophages, which a significant barrier successful therapeutic delivery.