Shape induced inhibition of phagocytosis of polymer particles.

作者: Julie A. Champion , Samir Mitragotri

DOI: 10.1007/S11095-008-9626-Z

关键词: Drug deliveryPhagocytosisPolymer particlePharmacology toxicologyBiophysicsParticleNanotechnologyMacrophageChemistry

摘要: Purpose To determine if particle shape can be engineered to inhibit phagocytosis of drug delivery particles by macrophages, which a significant barrier successful therapeutic delivery.

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