作者: Yu-Tzu Tai , Chirag Acharya , Gang An , Michele Moschetta , Mike Y. Zhong
DOI: 10.1182/BLOOD-2016-01-691162
关键词: Bone marrow 、 Osteoclast 、 Vascular endothelial growth factor A 、 Biology 、 Cytotoxic T cell 、 Cell growth 、 Cancer research 、 Transforming growth factor 、 Angiogenesis 、 Paracrine signalling
摘要: Here we show that overexpression or activation of B-cell maturation antigen (BCMA) by its ligand, a proliferation-inducing ligand (APRIL), promotes human multiple myeloma (MM) …