Raine eye health study: design, methodology and baseline prevalence of ophthalmic disease in a birth-cohort study of young adults.
作者： Seyhan Yazar , Hannah Forward , Charlotte M. McKnight , Alex Tan , Alla Soloshenko
DOI: 10.3109/13816810.2012.755632
关键词: Epidemiology 、 Pediatrics 、 Visual acuity 、 Research design 、 Eye disease 、 Young adult 、 Prospective cohort study 、 Cohort study 、 Cohort 、 Medicine
摘要: ABSTRACTPurpose: The Raine Eye Health Study (REHS) was conceived to determine the prevalence of and risk factors for eye disease in young adults, characterize ocular biometric parameters a adult cohort. This article summarizes rationale study design REHS outlines baseline ophthalmic this population.Methods: Western Australian Pregnancy Cohort (Raine) originated as randomized-controlled trial 2900 women recruited from state’s largest maternity hospital. Their offspring (N = 2868) have been followed at birth, ages 1, 2, 3, 5, 8, 10, 14, 17 20 years age prospective cohort study. DNA has collected participants genome-wide association studies. At 20-year follow-up completed comprehensive assessment that included visual acuity, orthoptic cycloplegic autorefraction, well several variables multiple photographs anterior poste...
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