Adrenal chromaffin cells as multipotential neurons for autografts.
作者： Nagesh K Mahanthappa , Fred H Gage , Paul H Patterson , None
DOI: 10.1016/S0079-6123(08)62587-X
关键词: Cholinergic 、 Neurite 、 Nerve growth factor 、 Adrenal chromaffin 、 Fibroblast growth factor 、 Chromaffin cell 、 Internal medicine 、 Conditioned medium 、 Endocrinology 、 Phenotype 、 Biology
摘要: The chromaffin cell grafts in the Parkinsonism models is used primarily as living depots of catecholamines. Because their phenotypic plasticity, however, cells have considerably more potential donor tissue than has been utilized heretofore. These can be maintained normal phenotype by addition corticosteroids, and they grow neurites when steroid removed nerve growth factor (NGF) or fibroblast (FGF) added. Moreover, appropriate conditioned medium (CM) supplied along with NGF, efficiency conversion neonatal into sympathetic neurons enhanced taken from adult rats also converted. In addition, cell-derived converted to cholinergic an instructive differentiation purified cultured heart converted, form functional synapses.
sci-hub.se 参考文章(50)
Laura E. Lillien, Philippa Claude, Nerve Growth Factor and glucocorticoids regulate phenotypic expression in cultured chromaffin cells from adult rhesus monkeys Experimental Cell Research. ,vol. 161, pp. 255- 268 ,(1985) , 10.1016/0014-4827(85)90083-7
Anders Bjo¨rklund, Ulf Stenevi, Experimental reinnervation of the rat hippocampus by grafted sympathetic ganglia I. Axonal regeneration along the hippocampal fimbria Brain Research. ,vol. 138, pp. 259- 270 ,(1977) , 10.1016/0006-8993(77)90744-2
J.A. Kessler, Differential regulation of peptide and catecholamine characters in cultured sympathetic neurons. Neuroscience. ,vol. 15, pp. 827- 839 ,(1985) , 10.1016/0306-4522(85)90081-8
S. C. Landis, Rat sympathetic neurons and cardiac myocytes developing in microcultures: correlation of the fine structure of endings with neurotransmitter function in single neurons. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 4220- 4224 ,(1976) , 10.1073/PNAS.73.11.4220
Philippa Claude, Isabel M. Parada, Kristin A. Gordon, Patricia A. D'Amore, John A. Wagner, Acidic fibroblast growth factor atimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long term survival factor Neuron. ,vol. 1, pp. 783- 790 ,(1988) , 10.1016/0896-6273(88)90126-2
D. I. Peterson, M. L. Price, C. S. Small, Autopsy findings in a patient who had an adrenal-to-brain transplant for Parkinson's disease Neurology. ,vol. 39, pp. 235- 235 ,(1989) , 10.1212/WNL.39.2.235
Sigrun Korsching, The role of nerve growth factor in the CNS Trends in Neurosciences. ,vol. 9, pp. 570- 573 ,(1986) , 10.1016/0166-2236(86)90179-7
PATRICK J. KELLY, J. ERIC AHLSKOG, JON A. van HEERDEN, STEPHEN W. CARMICHAEL, SUSAN L. STODDARD, GAYE N. BELL, Adrenal medullary autograft transplantation into the striatum of patients with Parkinson's disease. Mayo Clinic proceedings. ,vol. 64, pp. 282- 290 ,(1989) , 10.1016/S0025-6196(12)65248-3
George S Allen, R Stanley Burns, Noel B Tulipan, Robert A Parker, Adrenal Medullary Transplantation to the Caudate Nucleus in Parkinson's Disease: Initial Clinical Results in 18 Patients JAMA Neurology. ,vol. 46, pp. 487- 491 ,(1989) , 10.1001/ARCHNEUR.1989.00520410021016
M I Johnson, C D Ross, M Meyers, E L Spitznagel, R P Bunge, Morphological and biochemical studies on the development of cholinergic properties in cultured sympathetic neurons. I. Correlative changes in choline acetyltransferase and synaptic vesicle cytochemistry. Journal of Cell Biology. ,vol. 84, pp. 680- 691 ,(1980) , 10.1083/JCB.84.3.680