The Adrenal Medulla in MEN 2

作者: Arthur S. Tischler , Ronald A. DeLellis

DOI: 10.1007/978-3-662-21948-5_6

关键词: Multiple endocrine neoplasia type 2Familial medullary thyroid carcinomaMedullary cavityPheochromocytomaAdrenal medullaMedicineThyroid carcinomaPathologyChromaffin cellThyroid

摘要: The multiple endocrine neoplasia type 2 (MEN 2) syndromes are a fascinating group of proliferative disorders that classically involve both the adrenal medulla and thyroid C-cells. 1961 report by Sipple,1 then surgery resident, more than coincidental association between pheochromocytoma carcinoma focused attention on entity now known as MEN 2A. Subsequent studies Williams2 established carcinomas were medullary type. Several papers shortly thereafter led to recognition 2B apparent variants two classic subsequently described, recently reviewed.3 These include familial without carcinoma, pheochromocytoma.

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