作者: K. Mark Newbold , Fiona Macdonald , William H. Allum
关键词: Biology 、 Pathology 、 Cellular differentiation 、 Intestinal metaplasia 、 Foveolar cell 、 Gastritis 、 Atrophic gastritis 、 Stomach 、 Gastric mucosa 、 Columnar Cell 、 Pathology and Forensic Medicine
摘要: We have observed and defined morphometrically histochemically an entity composed of groups undifferentiated columnar cells on the interfoveolar crest gastric mucosa. These are clearly distinct from either normal foveolar or regenerative epithelial associated with ulcer healing. They show a close association atrophic gastritis, particularly in presence type 3 sulphomucin-secreting intestinal metaplasia. termed this tip lesion since it is only tips mucosal folds. This has not been described previously. propose that these precursors metaplasia may also provide link between variant adeno-carcinoma.