Absolute Asymmetric Synthesis: The Origin, Control, and Amplification of Chirality

摘要: Biomolecular homochirality, the origin of which is still a puzzle, has challenged scientists to design chemical systems that provide chiral molecules through absolute asymmetric synthesis and amplify small stereochemical bias in such systems. The photoresolution enantiomers helical-shaped, sterically overcrowded alkene 1 with circularly polarized light transduction information by triggering helical arrangement large collection achiral twisted nematic liquid crystalline phase (2) are examples control amplification chirality.