Coffee components and cardiovascular risk: beneficial and detrimental effects

作者: Justyna Godos , Francesca Romana Pluchinotta , Stefano Marventano , Silvio Buscemi , Giovanni Li Volti

DOI: 10.3109/09637486.2014.940287

关键词: Health benefitsCoffee consumptionFood scienceAntioxidantCaffeineBiologyLipid fractionHuman health

摘要: Coffee consists of several biological active compounds, such as caffeine, diterpenes, chlorogenic acids, and melanoidins, which may affect human health. The intake each compound depends on the variety coffee species, roasting degree, type brewing method serving size. bioavailability distribution its metabolites also contribute to mechanisms action. health benefits consumption regarding cardiovascular system metabolism mostly depend antioxidant compounds. In contrast, diterpenes caffeine produce harmful effects by raising lipid fraction affecting endothelial function, respectively. Studying mechanism action components help understanding whether coffee's impact is beneficial or hazardous. this article, we reviewed available information about compounds their Furthermore, risks for associated with will be discussed.

参考文章(150)
A. Suzuki, D. Kagawa, A. Fujii, R. Ochiai, I. Tokimitsu, I. Saito, Short- and long-term effects of ferulic acid on blood pressure in spontaneously hypertensive rats American Journal of Hypertension. ,vol. 15, pp. 351- 357 ,(2002) , 10.1016/S0895-7061(01)02337-8
G. Gross, E. Jaccaud, A.C. Huggett, Analysis of the content of the diterpenes cafestol and kahweol in coffee brews Food and Chemical Toxicology. ,vol. 35, pp. 547- 554 ,(1997) , 10.1016/S0278-6915(96)00123-8
Paola Vitaglione, Filomena Morisco, Giovanna Mazzone, Daniela Caterina Amoruso, Maria Teresa Ribecco, Antonietta Romano, Vincenzo Fogliano, Nicola Caporaso, Giuseppe D'Argenio, Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins. Hepatology. ,vol. 52, pp. 1652- 1661 ,(2010) , 10.1002/HEP.23902
Barry Halliwell, Lee H. Long, Tsin Pinn Yee, Sharon Lim, Ronan Kelly, Establishing biomarkers of oxidative stress: the measurement of hydrogen peroxide in human urine. Current Medicinal Chemistry. ,vol. 11, pp. 1085- 1092 ,(2004) , 10.2174/0929867043365404
Chi-Tai Yeh, Gow-Chin Yen, Effects of phenolic acids on human phenolsulfotransferases in relation to their antioxidant activity. Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 1474- 1479 ,(2003) , 10.1021/JF0208132
Orie YOSHINARI, Hideyo SATO, Kiharu IGARASHI, Anti-Diabetic Effects of Pumpkin and Its Components, Trigonelline and Nicotinic Acid, on Goto-Kakizaki Rats Bioscience, Biotechnology, and Biochemistry. ,vol. 73, pp. 1033- 1041 ,(2009) , 10.1271/BBB.80805
T G Kosmeijer-Schuil, B De Roos, S Meyboom, M B Katan, Absorption and urinary excretion of the coffee diterpenes cafestol and kahweol in healthy ileostomy volunteers Journal of Internal Medicine. ,vol. 244, pp. 451- 460 ,(1998) , 10.1046/J.1365-2796.1998.00386.X
Giuseppe Grosso, Stefano Marventano, Fabio Galvano, Andrzej Pajak, Antonio Mistretta, Factors associated with metabolic syndrome in a mediterranean population: role of caffeinated beverages. Journal of Epidemiology. ,vol. 24, pp. 327- 333 ,(2014) , 10.2188/JEA.JE20130166
Diana Gniechwitz, Nicole Reichardt, John Ralph, Michael Blaut, Hans Steinhart, Mirko Bunzel, Isolation and characterisation of a coffee melanoidin fraction Journal of the Science of Food and Agriculture. ,vol. 88, pp. 2153- 2160 ,(2008) , 10.1002/JSFA.3327
Kazuya KOZUMA, Shigemi TSUCHIYA, Jun KOHORI, Tadashi HASE, Ichiro TOKIMITSU, Antihypertensive Effect of Green Coffee Bean Extract on Mildly Hypertensive Subjects Hypertension Research. ,vol. 28, pp. 711- 718 ,(2005) , 10.1291/HYPRES.28.711