Transient receptor potential (TRP) channels in the airway: role in airway disease.
作者： M S Grace , M Baxter , E Dubuis , M A Birrell , M G Belvisi
DOI: 10.1111/BPH.12538
关键词: TRPV4 、 Pathogenesis 、 Context (language use) 、 Transient receptor potential channel 、 Lung 、 Anti-asthmatic Agent 、 TRPM8 、 TRPV1 、 Immunology 、 Medicine 、 Bioinformatics
摘要: Over the last few decades, there has been an explosion of scientific publications reporting the many and varied roles of transient receptor potential (TRP) ion channels in physiological and pathological systems throughout the body. The aim of this review is to summarize the existing literature on the role of TRP channels in the lungs and discuss what is known about their function under normal and diseased conditions. The review will focus mainly on the pathogenesis and symptoms of asthma and chronic obstructive pulmonary disease and the …
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