Acute myelopathy associated with primary infection with human immunodeficiency virus.

作者: D W Denning , J Anderson , P Rudge , H Smith

DOI: 10.1136/BMJ.294.6565.143

关键词: HyperreflexiaRashImmunologyGastroenterologyViral diseaseMyelopathyInternal medicineMyelitisAcquired immunodeficiency syndrome (AIDS)Sore throatSeroconversionMedicine

摘要: A 29 year old white homosexual man presented with a two and half week history of severe sore throat, fever, extreme fatigue. His symptoms did not respond to antibiotics. He had mild bilateral conjunctivitis, rash over his chest back, enlarged lymph nodes, but examination the nervous system yielded normal results. low total cell platelet counts. The results enzyme linked immunosorbent assay for human immunodeficiency virus (HIV) were equivocal when HIV IgM was detected in serum. Despite treatment ampicillin temperature remained high he developed abnormal neurological signs, including paraparesis hyperreflexia arms. isolated from lymphocytes blood cerebrospinal fluid. Over next six weeks patient improved discharged. Two months later signs persisted legs. Although various syndromes associated seroconversion have been described, this is probably first report myelopathy at time seroconversion.

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