作者: Gamal M. Hamad , Tarek H. Taha , Nehal M. El-Deeb , Ali M. A. Alshehri
DOI: 10.1007/S13197-015-1875-3
关键词: Helicobacter pylori 、 Myrrh 、 Antibiotics 、 Terpenoid 、 Gastritis 、 Traditional medicine 、 Antimicrobial 、 Medicine 、 Microbiology 、 Human pathogen 、 Phytochemical
摘要: Helicobacter pylori is a common human pathogen infecting about 30 % of children and 60 % adults worldwide. It responsible for diseases such as gastritis, peptic ulcer gastric cancer. H. treatment based on antibiotics with proton pump inhibitor, but therapy failure shown to be higher than 20 % essentially due an increasing in prevalence antibiotic-resistant bacteria, which has led the search alternative therapies. In this study, we discuss usage natural extracts mixture or complementary agents controlling infection so here, focused plant (Cloves, Pepper, Cumin, Sage, Pomegranate peel, Ginger, Myrrh Licorice). To that end, Phytochemical constituents detection like Tannins, Glycosides, Alkaloids, Flavonoids, Terpenoids, Saponins, Phenolic compounds, Reducing sugars, Volatile oils, Amino acids Proteins was demonstrated. Each extract examined individually combination its antimicrobial activity against pylori. Out used extracts, four mixes were prepared tested The antibacterial activities mixes, represented by diameter inhibition clear zone, recorded 21, 39, 23 28 mm. most potent mix (mix2) chosen mixed baby milk new infections babies.