Diagnosis of primary hepatic neoplasms by fine-needle aspiration cytology

摘要: This article describes the cytologic features of various primary hepatic neoplasms as seen in fine-needle aspirates. Hepatocellular carcinoma can be differentiated from metastatic by its tendency to recapitulate characteristics normal hepatocytes, namely, resemblance neoplastic cells liver cells, growth trabeculae, and bile production. Fibrolamellar hepatocellular is characterized larger, polygonal tumor with clearly defined cell outline, deeply eosinophilic granular cytoplasm, extremely large solitary nucleoli. Lamellae fibrocytes are dividing into small groups. adenoma focal nodular hyperplasia exhibit that benign-appearing or minimally atypical. Cholangiocarcinoma an adenocarcinoma cannot on purely morphologic grounds. Primary sarcoma exceptionally rare shows malignant spindle cells. Some inflammatory conditions such abscess, cysts, tuberculoma often present space-occupying lesions should included differential diagnosis neoplasm.