FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.

作者: Jing He , Huimin Xia , Jue Tang , Zhenjian Zhuo , Jiabin Liu

DOI: 10.1002/CTM2.395

关键词: Immune systemUbiquitinCancer researchNF-κBBlocking antibodyPhenotypeFatty acid-binding proteinChemistryFunction (biology)Neuroblastoma

摘要: … in blood-cell lineages but scarcely expressed in NB cell lines. Of note, FABP4 more highly … features of NB. To confirm the presence of TAMs in NB, we also stained the NB tissues for …

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