Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease.

摘要: Bisphosphonates are used for skeletal protection in osteoporosis, cancer bone metastasis, multiple myeloma, and Paget's disease of the bone; however, these drugs also have potential causing a number adverse effects. While do not limit bisphosphonate use, incidence events can be minimized if appropriate care is taken with their administration, by maintaining surveillance patient care, as discussed this review. valuable class potent anti-resorptive actions that make them ideal bone. It has become apparent, to cause care. We review range reactions therapy particular emphasis on recently identified association between long-term treatment osteonecrosis jaw. This potentially serious side effect seen mostly patients myeloma or breast metastases who receive intravenous treatment. etiology uncertain, strong dental pathology interventions highlights need close attention health group.