Treating ALK-positive lung cancer—early successes and future challenges

作者: D. Ross Camidge , Robert C. Doebele

DOI: 10.1038/NRCLINONC.2012.43

关键词: Drug resistanceOncologyCrizotinibInternal medicineAnaplastic lymphoma kinaseDrugLung cancerImmunologyMedicineAdverse effectDiseaseALK-Positive

摘要: … ALK to act as an oncogene in many different cancers, especially non-small-cell lung cancer (NSCLC) that has heightened interest in ALK … licensed ALK inhibitor for ALK-positive (ALK+) …

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