Multidrug Resistance-Associated Protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine Sulfoximine
作者： Ilhan Akan , Selma Akan , Hakan Akca , Burhan Savas , Tomris Ozben
关键词: Pharmacology 、 Multiple drug resistance 、 Glutathione peroxidase 、 Biology 、 Buthionine sulfoximine 、 HEK 293 cells 、 Multidrug Resistance-Associated Protein 1 、 Acetylcysteine 、 Glutathione 、 Transfection
摘要: … This is another proof that survival promoting action of NAC depends on GSH synthesis and … that NAC enhances MRP1-mediated vincristine resistance and this effect depends on GSH …
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