Risk of neoplasia in renal transplant patients
作者： N.J London , S.M Farmery , J.P.A Lodge , E.J Will , A.M Davidson
DOI: 10.1016/S0140-6736(95)92780-8
关键词: Pediatrics 、 Transplantation 、 Surgery 、 Population control 、 Kidney transplantation 、 Survival analysis 、 Neoplastic lesion 、 Renal transplant 、 Population 、 Medicine 、 Retrospective cohort study
摘要: Abstract Summary Renal allograft recipients are at an increased risk of neoplasia, although the extent problem has not been established in a typical European transplant population. To assess this we did comprehensive, retrospective study 918 patients transplanted one centre over 24 years. The (Leeds) serves Yorkshire and Humberside, region northern England with population 3·6 million. search, which made use six sources information, revealed 70 (7·6%) who had developed neoplastic lesion, 10 having more than type. More half (42) were cutaneous lesions (mostly squamous cell carcinomas). developing neoplasia first years after transplantation was calculated to be 14%. By 20 risen 40% compared 6% cumulative age-matched control (p full underestimated and, now that surviving longer, there is clear need for both lifelong surveillance closer investigation these patients.
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sci-hub.se 参考文章(15)
I Penn, THE CHANGING PATTERN OF POSTTRANSPLANT MALIGNANCIES International congress of the transplantation society. ,vol. 23, pp. 1101- 1103 ,(1991)
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
J.C. Pecqueux, A. Schwarz, K.P. Dieckmann, G. Offermann, Cancer Incidence in Patients on Chronic Dialysis and in Renal Transplant Recipients Urologia Internationalis. ,vol. 45, pp. 290- 292 ,(1990) , 10.1159/000281722
ISRAEL PENN, Cancers following cyclosporine therapy. Transplantation. ,vol. 43, pp. 32- 34 ,(1987) , 10.1097/00007890-198701000-00008
Sven Arvid Birkeland, Malignant tumors in renal transplant patients the scandia transplant material Cancer. ,vol. 51, pp. 1571- 1575 ,(1983) , 10.1002/1097-0142(19830501)51:9<1571::AID-CNCR2820510903>3.0.CO;2-S
INGEMAR BLOHMÉ, OLLE LARKÖ, Premalignant and malignant skin lesions in renal transplant patients. Transplantation. ,vol. 37, pp. 165- 167 ,(1984) , 10.1097/00007890-198402000-00010
M. K. Walz, K. H. Albrecht, W. Niebel, F. W. Eigler, De novo malignant tumors during drug immunosuppression. The findings following 1245 cadaveric kidney transplants in 1080 patients Deutsche Medizinische Wochenschrift. ,vol. 117, pp. 927- 934 ,(2008) , 10.1055/S-2008-1062393
M. Liddington, A. J. Richardson, R. M. Higgins, Z. H. Endre, V. A. Venning, J. A. Murie, P. J. Morris, Skin cancer in renal transplant recipients. British Journal of Surgery. ,vol. 76, pp. 1002- 1005 ,(2005) , 10.1002/BJS.1800761005
ArthurJ Matas, CarlM Kjellstrand, RichardL Simmons, TheodoreJ Buselmeier, JohnS Najarian, Increased incidence of malignancy during chronic renal failure. The Lancet. ,vol. 305, pp. 883- 886 ,(1975) , 10.1016/S0140-6736(75)91684-0
T. H. Mathew, N. Amiss, A. G. R. Sheil, A. P. S. Disney, De novo malignancy emerges as a major cause of morbidity and late failure in renal transplantation. Transplantation Proceedings. ,vol. 25, pp. 1383- 1384 ,(1993)