作者: Terje Raudsepp
DOI: 10.1016/J.CVEQ.2020.03.013
关键词: Gene 、 Genetics 、 Genetic testing 、 Susceptibility gene 、 Phenotype 、 Genetic heterogeneity 、 Pedigree chart 、 Genomics 、 Chromosome analysis 、 Medicine 、 Equine
摘要: Reproductive disorders are genetically heterogeneous and complex; available genetic tests limited to chromosome analysis 1 susceptibility gene. Cytogenetic should be the first test confirm or rule out chromosomal aberrations. No causative genes/mutations known. The only for stallion subfertility is based on a gene FKBP6. ongoing progress in equine genomics will improve status of testing. However, because subfertile phenotypes do not facilitate collection large numbers samples pedigrees, clinical causes many cases remain unknown, further requires constructive cross-talk between geneticists, clinicians, breeders, owners.