Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid
作者： Ofer Spiegelstein , Deanna L. Kroetz , René H. Levy , Boris Yagen , Sussan I. Hurst
关键词: Biochemistry 、 Structure–activity relationship 、 Microsomal epoxide hydrolase 、 Enzyme inhibitor 、 Microsome 、 Amide 、 Enzyme 、 Valnoctamide 、 Epoxide hydrolase 、 Chemistry 、 Stereochemistry
摘要: Purpose. The purpose of this study was to evaluate the in vitro inhibitory potency various amide analogues and derivatives valproicacid toward human microsomal epoxide hydrolase (mEH).
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