Role of surgical therapy in the management of gestational trophoblastic neoplasia
作者： Kyung Jin Eoh , Young Shin Chung , Ga Won Yim , Eun Ji Nam , Sunghoon Kim
DOI: 10.5468/OGS.2015.58.4.277
关键词: Uterine artery embolization 、 Nephrectomy 、 Hysterectomy 、 Surgery 、 Craniotomy 、 Wedge resection (lung) 、 Medicine 、 Curettage 、 Choriocarcinoma 、 Chemotherapy
摘要: OBJECTIVE: To evaluate the role of adjuvant surgical procedures in management gestational trophoblastic neoplasia (GTN). METHODS: In a retrospective review medical records at Severance Hospital, we identified 174 patients diagnosed with GTN between 1986 and 2006. Of patients, 129 (74%) were assigned to nonmetastatic group, 45 (26%) metastatic group; group 6 low-risk 39 high-risk group. Thirty-two underwent 35 as part treatment. The included hysterectomy, lung resection, craniotomy, uterine wedge suturing for bleeding, salpingo-oophorectomy, pretherapy dilatation curettage, adrenalectomy, nephrectomy, artery embolization. RESULTS: 32 who procedures, 28 (87%) survived. Eleven surgery chemoresistant disease after receiving one or more chemotherapy regimens. Twelve control tumor hemorrhage. Nine (81%) 11 survived, 8 salvage received further chemotherapy. 21 19 (90%) achieved remission. All three had resistant foci choriocarcinoma remission through pulmonary resection. CONCLUSION: Adjuvant especially hysterectomy resection disease, well hemorrhage, are pivotal GTN.
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