Pulmonary Fibrosis in Generalized Scleroderma: Report of a Case and Review of the Literature

摘要: A case of generalized progressive scleroderma, with roentgenologically visualized pulmonary involvement, is reported, and the essential features such cases that have been reported in English literature are tabulated discussed. Scleroderma lungs may clinically antedate development typical skin changes present picture chronic disease. This occurred approximately one-fourth reviewed. Roentgenograms a net-like interstitial fibrosis lower two-thirds lungs, sometimes associated multiple varying sized cysts. The fundamental pathological consist diffuse alveolar wall sclerosis obliteration, cystic changes, some cases, vascular narrowing due to involvement supporting connective tissue vessel walls. In obscure lung, scleroderma should be kept mind. para-aminobenzoic acid used treatment our was furnished by Wyeth, Incorporated, Philadelphia, Pennsylvania.