Immunohistochemistry in dermatopathology: a review of the most commonly used antibodies (part I).

作者: L. Fuertes , C. Santonja , H. Kutzner , L. Requena

DOI: 10.1016/J.ADENGL.2013.02.001

关键词: ImmunohistochemistryImmunoperoxidase TechniquesDermatopathologyAntibodyPathologyDifferential diagnosisMedicineHistopathology

摘要: Dermatopathology includes a long list of disorders, some which have very similar histopathology. Immunohistochemistry is an important auxiliary tool for diagnosis and differential diagnosis, predicting the outcome many skin tumors. It also main technique determining origin tissue or differentiation neoplastic cells. In cases, immunohistochemistry provides more accurate different processes that infiltrate skin. This review examines role in studying biological behavior majority tumors can involve We immunoperoxidase techniques, discuss utility most commonly used antibodies, highlight number diagnostic problems may be useful. each case, goal to reach specific definitive diagnosis. first part this review, we examine antibodies determine cell-differentiation profiles

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