Defective Fc receptor-mediated clearance in patients with primary biliary cirrhosis
作者： Kristina Nilsson Ekdahl , Lars Lööf , Anders Nyberg , Ulf R. Nilsson , Bo Nilsson
DOI: 10.1016/0016-5085(91)90736-5
关键词: Immunoglobulin A 、 Internal medicine 、 Immunology 、 Bilirubin 、 Primary biliary cirrhosis 、 Cirrhosis 、 Antibody 、 Fc receptor 、 Gastroenterology 、 Immunoglobulin G 、 Alcoholic liver disease 、 Biology
摘要: Fc receptor-mediated clearance of immunoglobulin G-coated autologous erythrocytes was studied in patients with primary biliary cirrhosis (n = 14), alcoholic liver 5) and healthy reference individuals 14). The mean half-life the sensitized significantly prolonged (85 +/- 25 minutes; P less than 0.001) compared corresponding value (16 2 minutes) (20 5 minutes), respectively. No correlation between rate age, histopathology, or serum levels bilirubin, aminotransferases, G, A, Clq binding C3-containing immune complexes found. results presented here indicate a profound disturbance function cirrhosis.
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