Temporal differentiation across a West-European Y-chromosomal cline - genealogy as a tool in human population genetics

摘要: The pattern of population genetic variation and allele frequencies within a species are unstable changing over time according to different evolutionary factors. For humans, it is possible combine detailed patrilineal genealogical records with deep Y-chromosome (Y-chr) genotyping disentangle signals historical structures because the exponential increase in data. To test this approach, we studied temporal 'autochthonous' micro-geographical structure region Brabant Belgium Netherlands (Northwest Europe). Genealogical data 881 individuals from Northwest Europe were collected, which 634 family trees showed residence for at least one generation. Y-chr participants was investigated using 110 Y-SNPs 38 Y-STRs linked particular locations on specific periods based records. Significant distribution detected through north-south gradient sub-haplogroup R1b1b2a1 (R-U106), next an opposite trend R1b1b2a2g (R-U152). R-U106 faded even became totally invisible during Industrial Revolution first half nineteenth century. Therefore, 200 years required study small-scale Western Europe.