作者: Maria Ilia
DOI: 10.1016/S0074-7742(04)59018-9
关键词: TAF2 、 POU domain 、 GATA transcription factor 、 TCF4 、 Response element 、 Neuroscience 、 Homeobox 、 Biology 、 NKX-homeodomain factor 、 E-box
摘要: A variety of neurological disorders may have their origin during development the central nervous system. Defects consistent with abnormal brain been reported in schizophrenia. These include faulty neuronal migration,altered spatial distribution, and absence significant gliosis. abnormalities adult are allocated to developmental processes thus indicate a basis for Our way toward understanding schizophrenia pathology has consider genes that regulate normal development. One such family is POU homeobox transcription factors. This chapter reviews domain proteins, focusing on III gene, Oct-6, along its potential relevance