Development of a quercetin-loaded nanostructured lipid carrier formulation for topical delivery.

作者: Guo Chen-yu , Yang Chun-fen , Li Qi-lu , Tan Qi , Xi Yan-wei

DOI: 10.1016/J.IJPHARM.2012.03.042

关键词: Drug carrierNanoparticlePermeability (electromagnetism)Particle sizeZeta potentialIn vivoBiomedical engineeringPermeationPharmacologyEmulsionChemistry

摘要: The main objective of this study was to evaluate the potential of Quercetin-loaded nanostructured lipid carriers (QT-NLCs) as a topical delivery system. QT-NLCs were prepared by the …

参考文章(35)
HouLi Li, XiaoBin Zhao, YuKun Ma, GuangXi Zhai, LingBing Li, HongXiang Lou, Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles. Journal of Controlled Release. ,vol. 133, pp. 238- 244 ,(2009) , 10.1016/J.JCONREL.2008.10.002
Carmelo Puglia, Francesco Bonina, Giuseppe Trapani, Massimo Franco, Maurizio Ricci, Evaluation of in vitro percutaneous absorption of lorazepam and clonazepam from hydro-alcoholic gel formulations. International Journal of Pharmaceutics. ,vol. 228, pp. 79- 87 ,(2001) , 10.1016/S0378-5173(01)00806-7
Yang Yue, Huafeng Zhou, Guanlan Liu, Yan Li, Zemin Yan, Mingxing Duan, The advantages of a novel CoQ10 delivery system in skin photo-protection International Journal of Pharmaceutics. ,vol. 392, pp. 57- 63 ,(2010) , 10.1016/J.IJPHARM.2010.03.032
Larry A Wheeler, Angelika Aswad, Michael J Connor, Nicholas Lowe, Depletion of cutaneous glutathione and the induction of inflammation by 8-methoxypsoralen plus UVA radiation. Journal of Investigative Dermatology. ,vol. 87, pp. 658- 662 ,(1986) , 10.1111/1523-1747.EP12456380
Stephen D Skaper, Michele Fabris, Vanni Ferrari, Maurizio Dalle Carbonare, Alberta Leon, Quercetin Protects Cutaneous Tissue-Associated Cell Types Including Sensory Neurons From Oxidative Stress Induced By Glutathione Depletion: Cooperative Effects of Ascorbic Acid Free Radical Biology and Medicine. ,vol. 22, pp. 669- 678 ,(1997) , 10.1016/S0891-5849(96)00383-8
Yanjun Zhao, Marc B. Brown, Stuart A. Jones, Pharmaceutical foams: are they the answer to the dilemma of topical nanoparticles? Nanomedicine: Nanotechnology, Biology and Medicine. ,vol. 6, pp. 227- 236 ,(2010) , 10.1016/J.NANO.2009.08.002
Ru Fang, Ruifang Hao, Xia Wu, Qi Li, Xiaojing Leng, Hao Jing, Bovine serum albumin nanoparticle promotes the stability of quercetin in simulated intestinal fluid. Journal of Agricultural and Food Chemistry. ,vol. 59, pp. 6292- 6298 ,(2011) , 10.1021/JF200718J
J.V. Formica, W. Regelson, Review of the biology of quercetin and related bioflavonoids Food and Chemical Toxicology. ,vol. 33, pp. 1061- 1080 ,(1995) , 10.1016/0278-6915(95)00077-1