Antiepileptic drugs and memory

作者: Gholam K. Motamedi , Kimford J. Meador

DOI: 10.1016/J.YEBEH.2004.03.006

关键词: Subjective perceptionMoodEpilepsyPsychologyClinical psychologyImpaired memoryNeurocognitiveMemory impairmentHealthy volunteersCognitionPsychiatry

摘要: Impaired memory is among the most common complaints of patients with epilepsy. Multiple factors contribute to impairment in Thus, delineation effects antiepileptic drugs (AEDs) on clinical populations faces methodological difficulties. Further, subjective perception problems by influenced mood. However, there evidence from animal and healthy volunteer studies supporting an independent potential for AEDs impair memory. Differential AED have been observed, may interact focal brain lesions. Memory a greater concern at age extremes, although AEDs, especially newer agents, not thoroughly studied these populations. Well-controlled are needed understand underlying mechanisms further delineate magnitude relative

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