Is There a Relation between EEG-Slow Waves and Memory Dysfunction in Epilepsy? A Critical Appraisal

摘要: Is there a relationship between peri-ictal slow waves, loss of consciousness, memory, and wave sleep, in patients with different forms epilepsy? We hypothesize that mechanisms which result activity as detected by the electroencephalogram could negatively affect memory processes. Slow waves (≤ 4 Hz) can be found seizures impairment consciousness also occur focal without but inhibited access to functions. Peri-ictal are regarded dysfunctional probably caused essential disturb consolidation entries these patients. This is strong contrast physiological during deep thought group memory-consolidating fast oscillatory activity. In epilepsy, may not only correlate clouding epiphenomenon interfere normal brain function wider range. These have transient impacts on such temporary inhibition systems, altered patterns hippocampal-neocortical interactions or disturbed cross-frequency coupling oscillations. addition, repeated tonic-clonic over years uncontrolled chronic epilepsy cause progressive cognitive decline. hypothesis assessed long term prospective studies. studies disentangle reversible short-term seizures, seizures. Chronic lead irreversible impairment. contrast, short do necessarily decline significantly impaired performance.