Procyanidine resists the fibril formation of human islet amyloid polypeptide.

作者: Weihong Du , Jufei Xu , Xiangyi Huang , Ting Zheng , Guowei Yin

DOI: 10.1016/J.IJBIOMAC.2021.05.030

关键词: FibrilNeurodegenerationIsletDownregulation and upregulationAmyloidCytotoxicityChemistryBiophysicsPeptideViability assay

摘要: … type II diabetes mellitus (T2DM). Bioflavonoids have been used in the neurodegeneration and diabetes … When 100 μM lipidosome were treated with 20 μM peptide and fivefold excess of …

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