Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men.

作者: Merrill F. Elias , Lisa M. Sullivan , Penelope K. Elias , Ramachandran S. Vasan , Ralph B. D’Agostino

DOI: 10.1016/J.JSTROKECEREBROVASDIS.2006.05.009

关键词: Atrial fibrillationGerontologyCognitionDementiaStrokeOffspringRecallEffects of sleep deprivation on cognitive performancePhysical therapyFramingham Risk ScoreMedicine

摘要: The purpose of this study was to investigate the association atrial fibrillation (AFIB) with multiple measures cognitive performance in a large community-based sample extensively characterized for vascular risk factors. Our primary analysis included 1011 Framingham Offspring Study (Framingham, Mass) men, mean age = 61.0 (37-89) years, free clinical stroke and dementia. Using multivariable linear regression models, we related presence (n 59) versus absence 952) AFIB men global measure specific abilities assessed an average 8 months after surveillance period. Adjusting age, education, cardiovascular factors, disease, exhibited significantly lower levels compared normal sinus rhythm. Men on ability including Similarities (abstract reasoning), Visual Reproductions-Immediate Recall, Reproductions-Delayed Organization, Logical Memory-Delayed Trail Making A (scanning tracking) B (scanning, tracking, executive functioning). Further studies leading better understanding mechanisms underlying relation between are important.

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