Malnutrition and Cachexia in Heart Failure.

作者: Adam Rahman , Syed Jafry , Khursheed Jeejeebhoy , A. Dave Nagpal , Barbara Pisani

DOI: 10.1177/0148607114566854

关键词: Tumor necrosis factor alphaMalnutritionCachexiaAppetiteIntensive care medicineWastingHeart failureMedicineSystemic inflammationOrgan transplantation

摘要: Heart failure is a growing public health concern. Advanced heart failure is frequently associated with severe muscle wasting, termed cardiac cachexia. This process is driven by systemic inflammation and tumor necrosis factor in a manner common to other forms of disease‐related wasting seen with cancer or human immunodeficiency virus. A variable degree of malnutrition is often superimposed from poor nutrient intake. Cardiac cachexia significantly decreases quality of life and survival in patients with heart failure. This review …

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