作者: Adam Rahman , Syed Jafry , Khursheed Jeejeebhoy , A. Dave Nagpal , Barbara Pisani
关键词: Tumor necrosis factor alpha 、 Malnutrition 、 Cachexia 、 Appetite 、 Intensive care medicine 、 Wasting 、 Heart failure 、 Medicine 、 Systemic inflammation 、 Organ transplantation
摘要: Heart failure is a growing public health concern. Advanced heart failure is frequently associated with severe muscle wasting, termed cardiac cachexia. This process is driven by systemic inflammation and tumor necrosis factor in a manner common to other forms of disease‐related wasting seen with cancer or human immunodeficiency virus. A variable degree of malnutrition is often superimposed from poor nutrient intake. Cardiac cachexia significantly decreases quality of life and survival in patients with heart failure. This review …