ISfinder: the reference centre for bacterial insertion sequences.

作者: Patricia Siguier , Jocelyne Pérochon , L Lestrade , Jacques Mahillon , Michael Chandler

DOI: 10.1093/NAR/GKJ014

关键词: Information retrievalBiologyGenomeHidden Markov modelThe InternetBacterial genome sizeGeneticsBackground informationCoding (social sciences)Insertion sequenceDNA sequencing

摘要: ISfinder (www-is.biotoul.fr) is a dedicated database for bacterial insertion sequences (ISs). It has superseded the Stanford reference center. One of its functions to assign IS names and provide focal point coherent nomenclature. also repository ISs. Each new indexed together with information such as DNA sequence open reading frames or potential coding sequences, ends element target sites, origin distribution bibliography where available. Another objective continuously monitor ISs updated comprehensive groupings families some insight into their phylogenies. The site contains extensive background on transposons in general. Online tools are gradually being added. At present an online Blast facility against entire bank But additional features will include alignment capability, PsiBLAST HMM profiles. includes section genomes involved annotating content these genomes. Finally, this currently recommended by several microbiology journals registration elements before publication.

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