Diagnosis and Treatment Options of Spinal Metastases.

摘要: Cancer patients with spinal metastases are a diagnostic and treatment challenge for the clinician. This must be addressed through multidisciplinary, multimodal, individualized management. The presence of tumor cells in bone results homeostatic disruption between formation remodeling. Bone destruction is late event lytic metastasis, starting when proliferate; this turn activates osteoclasts, seen as trabecular imaging studies. There may excessive increased formation, which produce blastic lesions. scintigraphy currently most widely used method considered reference test diagnosis metastasis. However, we believe that near future positron emission tomography associated to computed 18F-NaF, or magnetic resonance using diffusion-weighted whole-body background body signal suppression, will replace due their improved accuracy. These new tools help prevent metastasis complications such as: intractable pain; cord cauda equina compression; hypercalcemia; pathological fractures; instability. With regards treatment, it can uni- depending on type number metastases. Among types available chemotherapy, radiotherapy, invasive procedures. prognosis patient survival depends histopathology primary tumor, neurological deficits