Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio

作者: Yu-Song Ding , Shu-Xia Guo , Ru-Lin Ma , Shu-Gang Li , Heng Guo

DOI: 10.1155/2015/607364

关键词: Logistic regressionReceiver operating characteristicInsulin resistanceInternal medicineMetabolic syndromeInterleukin 6BiologyPopulationEndocrinologyBiomarker (medicine)Adiponectin

摘要: This study aimed at determining whether the adiponectin to HOMA-IR (A/H) ratio is associated with MetS and components comparing diagnostic efficacy of adiponectin, HOMA-IR, A/H in healthy, middle-aged participants. was assessed 1628 Kazakh participants (men, 768; women, 860). The associations between were examined using logistic regression analysis receiver operating characteristic (ROC) curves. Our results show that may be a better marker for than either or alone, it serve as an important biomarker determine increased risk healthy population.

参考文章(33)
David Grundy, Serotonin and sensory signalling from the gastrointestinal lumen The Journal of Physiology. ,vol. 575, pp. 1- 2 ,(2006) , 10.1113/JPHYSIOL.2006.113472
T.M. Ahonen, J.T. Saltevo, H.J. Kautiainen, E.A. Kumpusalo, M.J. Vanhala, The association of adiponectin and low-grade inflammation with the course of metabolic syndrome Nutrition Metabolism and Cardiovascular Diseases. ,vol. 22, pp. 285- 291 ,(2012) , 10.1016/J.NUMECD.2010.07.001
Qin Zhuo, Zhiqiang Wang, Ping Fu, Jianhua Piao, Yuan Tian, Jie Xu, Xiaoguang Yang, Comparison of adiponectin, leptin and leptin to adiponectin ratio as diagnostic marker for metabolic syndrome in older adults of Chinese major cities. Diabetes Research and Clinical Practice. ,vol. 84, pp. 27- 33 ,(2009) , 10.1016/J.DIABRES.2008.12.019
Ji Eu Yun, Soyoung Won, Yejin Mok, Wenying Cui, Heejin Kimm, Sun Ha Jee, Association of the leptin to high-molecular-weight adiponectin ratio with metabolic syndrome. Endocrine Journal. ,vol. 58, pp. 807- 815 ,(2011) , 10.1507/ENDOCRJ.K11E-084
Naveed Sattar, Alex McConnachie, A Gerald Shaper, Gerard J Blauw, Brendan M Buckley, Anton J de Craen, Ian Ford, Nita G Forouhi, Dilys J Freeman, J Wouter Jukema, Lucy Lennon, Peter W Macfarlane, Michael B Murphy, Chris J Packard, David J Stott, Rudi G Westendorp, Peter H Whincup, James Shepherd, S Goya Wannamethee, Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies The Lancet. ,vol. 371, pp. 1927- 1935 ,(2008) , 10.1016/S0140-6736(08)60602-9
Yoshifumi Saisho, Hiroshi Hirose, Rachel Roberts, Takayuki Abe, Hiroshi Kawabe, Hiroshi Itoh, C-Reactive Protein, High-Molecular-Weight Adiponectin and Development of Metabolic Syndrome in the Japanese General Population: A Longitudinal Cohort Study PLoS ONE. ,vol. 8, pp. e73430- ,(2013) , 10.1371/JOURNAL.PONE.0073430
B Singh, S Arora, B Goswami, V Mallika, None, Metabolic syndrome: A review of emerging markers and management Diabetes & Metabolic Syndrome: Clinical Research & Reviews. ,vol. 3, pp. 240- 254 ,(2009) , 10.1016/J.DSX.2009.04.012
Patricio López-Jaramillo, Diego Gómez-Arbeláez, Jose López-López, Cristina López-López, Javier Martínez-Ortega, Andrea Gómez-Rodríguez, Stefany Triana-Cubillos, The role of leptin/adiponectin ratio in metabolic syndrome and diabetes Hormone Molecular Biology and Clinical Investigation. ,vol. 18, pp. 37- 45 ,(2014) , 10.1515/HMBCI-2013-0053
S. M. Haffner, C. Gonzalez, H. Miettinen, E. Kennedy, M. P. Stern, A prospective analysis of the HOMA model : The Mexico City diabetes study Diabetes Care. ,vol. 19, pp. 1138- 1141 ,(1996) , 10.2337/DIACARE.19.10.1138
YuSong Ding, ShuGang Li, Ru-Lin Ma, Heng Guo, JingYu Zhang, Mei Zhang, JiaMing Liu, ShuXia Guo, Association of homeostasis model assessment of insulin resistance, adiponectin, and low-grade inflammation with the course of the metabolic syndrome Clinical Biochemistry. ,vol. 48, pp. 503- 507 ,(2015) , 10.1016/J.CLINBIOCHEM.2015.02.005