Use of high-volume haemodiafiltration in patients with refractory septic shock and acute kidney injury

摘要: Background. High-volume haemofiltration (HVHF) has been used successfully in animal models with sepsis, and preliminary data have shown that this technique may improve the haemodynamics patients refractory septic shock. We high-volume continuous venovenous haemodiafiltration (CVVHDF) acute kidney injury (AKI) shock to evaluate their outcome when compared prognosis predicted by scores of severity. Methods. This is a cohort study Medical Surgical Intensive Care Unit. Fifty-five AKI were included study. Results. CVVHDF was started requiring norepinephrine dose >0.2 µg/kg/min. classified according RIFLE criteria. Treatment implemented within first 24 h dialysis 70 mL/kg/h until reversal or death. treated an observed mortality 63%, similar APACHE II SAPS scores. Conclusion. Survival rate our highvolume identical survival severity haemodiafiltraton applicable severely ill but does not confer any clear advantage terms survival. therapy should be on routine basis