Upregulation of Interleukin 35 in Patients With Endometriosis Stimulates Cell Proliferation.

作者: Chun Zhang , Zheng Peng , DeYing Ban , Yi Zhang

DOI: 10.1177/1933719117715123

关键词: EndometriosisAndrologyEndometrial biopsyStromal cellInterleukinOvarian EndometriosisDownregulation and upregulationInterleukin 35MedicinePeritoneal fluid

摘要: In this study, we investigated the expression of interleukin 35 (IL-35) and its receptors in endometriosis, analyzed function IL-35 primary culture model endometrial stromal cells (ESCs), evaluated their clinicapathological significance. Peripheral blood (PB) peritoneal fluid (PF) were collected from 37 women with endometriosis 24 control women. The ectopic endometrium was obtained patients undergoing laparoscopic surgery. eutopic normal by biopsy. Levels PB PF enzyme-linked immunosorbent assay. Women had higher levels compared to controls both PF. n increased advanced stage those early stages A significant upregulation observed ovarian accompanied pelvic implants (PI) without PI The...

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